Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling

New paper on “Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling” published in Nature Communications by KOKI Scientists

Auro Science News

Researcher from the IEM-HAS discovered that back-propagating action potentials are not simply digital feedback signals in dendrites but also carry analogue information about the overall state of neurons. Using dendritic recordings, calcium imaging and glutamate-uncaging methods they showed that the analogue information about the somatic membrane potential modulate the dendritic action potential waveforms and local calcium influx enabling analog state-dependent long-term synaptic plasticity.

Brunner & Szabadics (2016) Nat Commun

Full article: Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling