N-STORM image

New paper on “Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke” published in Nature Communications by hungarian scientists

Auro Science News

“We show that selective elimination of microglia results in dysregulated neuronal activity and increased brain injury after experimental stroke in mice. Microglia-neuron interactions were visualized by N-STORM super-resolution microscopy, which revealed the formation of a direct contact between microglial processes and the neuronal cell body and identified clusters of microglial P2Y12 receptors at microglia-neuron contact sites. Neurons: magenta, P2Y12 confocal: blue, P2Y12 STORM: cian.”

Photo: Barbara Orsolits

Source: Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke